Catecholamines are produced in chromaffin cells in the medulla of the adrenal gland, from tyrosine , a non-essential amino acid derived from food or produced from phenylalanine in the liver. The enzyme tyrosine hydroxylase converts tyrosine to L-DOPA in the first step of catecholamine synthesis. L-DOPA is then converted to dopamine before it can be turned into noradrenaline. In the cytosol , noradrenaline is converted to epinephrine by the enzyme phenylethanolamine N-methyltransferase (PNMT) and stored in granules. Glucocorticoids produced in the adrenal cortex stimulate the synthesis of catecholamines by increasing the levels of tyrosine hydroxylase and PNMT.  
Estrogens -- particularly estradiol -- participate in a large number of vital processes in your body. In addition to their well-known roles in sexual differentiation and reproduction, estrogens are essential for normal brain development during fetal life, and they help support brain function during adulthood. Estrogens help maintain the integrity of your skeleton, skin and blood vessels, and they are instrumental in lipid metabolism. The physiologic necessity of estrogens is demonstrated in the number of organs and tissues that produce and respond to these important hormones.