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When we compared all moisturisers against no moisturiser or control, overall, participants considered moisturisers to be more than twice as effective in improving eczema than no moisturiser or control (5 studies), and more effective for itch (7 studies). Participants in both treatment arms reported comparable satisfaction (3 studies). According to physicians, moisturisers decreased eczema severity more than the control (12 studies), and led to fewer flares (6 studies). There were no differences between groups for the number of adverse events reported.