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Now you understand what you need to do and how you need to do it, but you still don’t have the proper doses or full time frame for your post cycle therapy treatment and that’s the final point of our discussion. While Nolvadex and Clomid can work equally as well, they will only work equally as well if they are dosed properly. This is where many fail when they use Clomid as Nolvadex is much stronger on a per milligram basis. For example, with 40mg of Nolvadex, for Clomid to match it you need 150mg. As for hCG dosing, 500iu to 1,000iu per day every day for 10 straight days is your plan and implemented precisely as discussed above. Once the hCG therapy is complete, you will start your Nolvadex therapy at 40mg per day or Clomid at 150mg per day; whichever you choose, you will continue it for two weeks. Once the two weeks is complete, you will complete two more weeks this time with a Nolvadex dosing at 20mg per day or a Clomid dosing at 100mg per day. No, you’re not done yet, you will complete one more week at 10mg per day for Nolvadex or 50mg per day with Clomid and add in an additional week at the same dose if you feel it is necessary.
Bapineuzumab, a humanized anti-aβ MAB, is directed against the N-terminus of Aβ. Phase II clinical trials of Bapineuzumab in mild to moderate AD patients resulted in reduced Aβ concentration in the brain. However, in patients with increased apolipoprotein (APOE) e4 carriers, Bapineuzumab treatment is also accompanied by vasogenic edema ,  a cytotoxic condition where the blood brain barrier has been disrupted thereby affecting white matter from excess accumulation of fluid from capillaries in intracellular and extracellular spaces of the brain.  In Phase III clinical trials, Bapineuzumab treatment is associated with reduced rate of accumulation of Aβ in the brain in APOE e4 patients, and no significant reduction of Aβ concentration in APOE e4 patients and non-APOE e4 patients. Therefore, Aβ plaque concentration were not reduced, and there is no significant clinical benefits in cognitive functioning. Bapineuzumab was discontinued after failing in Phase III clinical trial.