Yes it will raise your blood pressure, like all steroids. That is one of the factors that can cause anxiety, lethargy, moodiness... I monitor my bp and take fish oil and low dose aspirin so that keeps it in check. As long as you have everything else in your cycle in check, you should see no real side effects from tbol. It does not lower sex drive, it does not cause insomnia. I felt like an animal on it! It doesn't aromatize at a high rate like dbol, you won't gain water weight fast, but more slow steady quality gains. It made me way more defined and vascular. Strength and pumps are awesome on it. I ran it at 50mg, that dose seemed great for me.