Ninety-five percent of all carcinoids are found in the appendix, rectum, or small intestine. 9 The remainder arise outside of the intestinal tract (., in the ovary or testis). In general, the larger the primary tumor, the greater the likelihood of metastasis, which provides prognostic implications. 9 Carcinoids of the appendix and rectum rarely manifest with the carcinoid syndrome. Forty percent to 50% of patients with carcinoids of the small intestine or proximal colon have manifestations of the carcinoid syndrome. 10 Tumors that secrete their hormonal product into the portal venous system do not cause flushing, because the released amines are inactivated by the liver. In contrast, liver metastases may escape hepatic inactivation and deliver their product directly into the systemic circulation, hence causing flushing. 9 Pulmonary or ovarian carcinoids release pharmacologic products directly into the venous circulation, bypassing the portal system, and can therefore cause symptoms without metastasizing to the liver. 1,10
There are possible side effects of Testosterone Enanthate use, but we will find they are extremely easy to avoid for the healthy adult male. When we refer to the healthy adult male we are excluding the issue of low testosterone. For the low level patient, the probability of side effects will be extremely low. In such a case, the individual is merely replacing what he’s lacking and nothing more. For the performance athlete, the side effects of Testosterone Enanthate will carry a greater probability, but should still be very controllable. Most men can tolerate high levels of testosterone very well. However, as with many things in life individual response and sensitivity issues will play a role. This is not unique to Testosterone Enanthate but holds true with all things we put in our body. In order to understand the possible side effects of Testosterone Enanthate, we have broken them down into their separate categories along with all the information you’ll need.