– Use in Bone marrow edema (internal swelling in the bone):
bone marrow edema is common in osteitis pubis. Bone marrow edema in other areas has responded to biphosphonates (of which pamidronate is a member):
Rheumatol Int. 2013 Jun;33(6):1397-402.
Bisphosphonates or prostacyclin in the treatment of bone-marrow oedema syndrome of the knee and foot.
Baier C1, Schaumburger J, Götz J, Heers G, Schmidt T, Grifka J, Beckmann J.
They found: “Regarding bisphosphonates, four patients described pain release after the first infusion, another three after the second treatment and another two not until the third application,
leaving one non-responder in the bisphosphonate treatment group.”
This is exactly what happened to me. I had perfectly healthy 18 year old cartilage in my 50s. I went to my orthopedic doctor for a patellar tracking problem in both knees that could be corrected with simple exercise. But in the meantime my doctor gave me many cortisone injections. 2 years later I was bone on bone. I was and am still absolutely horrified as I have no knee damage history. I became a cripple overnight. I pursued legal action against the drug company who makes the cortisone but it couldn’t be proven unfortunately. Regenexx has helped tremendously to get my life back! I am back to hiking 3 days a week. Thank you Regenexx. You are a God send!!