Much of our developed methodology has been, or is being applied in complex natural product synthesis to demonstrate the power of the methodology, to uncover unsolved synthetic problems and to further improve the training of the Part II, PhD or post-doctoral researcher on the project. Some completed targets from our group include tarchonanthuslactone, Equisetin and Rolipram. On going total synthesis programs are targeting presilphiperfol-1-ene, subincanadine, nakadomarin A, buphanamine, manzamine A and daphniyunnine B. All the major synthetic problems to presilphiperfol-1-ene, subincanadine, nakadomarin A and buphanamine have been overcome and it is anticipated that their syntheses will be completed shortly.
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