In another study, Whittington et al. reviewed 8 hCG assays for their ability to detect 5 of the 6 WHO International Reference Reagents (IRR): intact hCG, nicked hCG, β-hCG, nicked β-hCG, and hCGβcf. 4 Each IRR was spiked into normal, hCG-free, human serum, then assayed. All 8 assays accurately detected intact hCG and nicked hCG, while 7 of the 8 accurately reported the β-hCG and nicked β-hCG levels. The detection of hCGβcf was, however, much less than desired as only 2 of the 8 assays detected it at all, and both of those appreciably under-reported the actual levels.
This entry describes 4 <p> This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p> <a href='/help/alternative_products' target='_top'> More...</a> </p> isoforms i produced by alternative splicing . Align Add to basket Added to basket